2-Bromobiphenyl
Description Uses synthesis- Product Name
- 2-Bromobiphenyl
- CAS No.
- 2052-07-5
- Chemical Name
- 2-Bromobiphenyl
- Synonyms
- 2-bromo-1,1'-biphenyl;pbb 1;PBB NO 1;2-Brombiphenyl;o-Bromobiphenyl;2-BROMODIPHENYL;2-BROMOBIPHENYL;2- Bromobenzene;BROMOBIPHENYL(2-);Biphenyl, 2-bromo-
- CBNumber
- CB5733745
- Molecular Formula
- C12H9Br
- Formula Weight
- 233.1
- MOL File
- 2052-07-5.mol
2-Bromobiphenyl Property
- Melting point:
- 1.5-2 °C(lit.)
- Boiling point:
- 297-298 °C(lit.)
- Density
- 1.352 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.628(lit.)
- Flash point:
- 113 °C
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly, Heated), Methanol (Slightly)
- form
- Liquid
- Specific Gravity
- 1.352
- color
- Clear colorless
- Water Solubility
- Insoluble
- BRN
- 1863156
- Stability:
- Stable, but light sensitive. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 2052-07-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,1'-Biphenyl, 2-bromo-(2052-07-5)
- EPA Substance Registry System
- 2-Bromobiphenyl (2052-07-5)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 23-24/25-37/39-26-36
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29036990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H372Causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 252247
- Product name
- 2-Bromobiphenyl
- Purity
- 96%
- Packaging
- 5g
- Price
- $134
- Updated
- 2024/03/01
- Product number
- B21840
- Product name
- 2-Bromobiphenyl, 98%
- Packaging
- 1g
- Price
- $23.1
- Updated
- 2023/06/20
- Product number
- B21840
- Product name
- 2-Bromobiphenyl, 98%
- Packaging
- 5g
- Price
- $73.1
- Updated
- 2023/06/20
- Product number
- B21840
- Product name
- 2-Bromobiphenyl, 98%
- Packaging
- 25g
- Price
- $268
- Updated
- 2023/06/20
- Product number
- B680550
- Product name
- 2-Bromo-1,1''-biphenyl
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
2-Bromobiphenyl Chemical Properties,Usage,Production
Description
2-Bromobiphenyl is an important intermediate, which can be used to synthesize 2,2'-dibromo-9,9'-spirobifluorene, 3-bromo-9-(9-phenylfluoren-9-yl)carbazole and phenanthrene compounds.
Uses
2-Bromobiphenyl can be used as reference compound to investigate extraction efficiency of solid-phase microextraction fibers, based on methacrylic acid-trimethylolpropanetrimethacrylate copolymers.
synthesis
Carry out all catalytic reactions in reaction vessels open to the air. Charge a round-bottom flask with the newly purchased or freshly recrystallized aryl boronic acid (2.0 mmol), 1,2-dibromobenzene, powdered K3PO4 (2.2 mmol) and toluene (2.5 mL) of technical quality. Stir the mixture vigorously. Heat the mixture to 80 °C for 10 minutes. Add (0.2 mol%) of catalyst by syringe as a 2.5 ml of toluene solution to the mixture. Take the samples periodically from the reaction mixture. Quench the reaction with water. Extract the mixture with ethyl acetate. Analyze the reaction by GC-MS. At the end of catalytic reaction, cool the reaction mixture to room temperature. Quench the mixture with water (adjusted to an appropriate pH when biaryls with acidic or basic groups has to be extracted). Extract the mixture with ethyl acetate (3×40 mL). Dry the combined extracts (MgSO4). Evaporate the combined extracts to dryness. Purify the crude material by flash chromatography on silica gel.
Physical properties
2-Bromobiphenyl has a melting point of 1.5-2 °C, so it is a colorless liquid at room temperature. It boils at 297-298 °C. Its density at 25℃ is 1.352 g/mL. In general, 2-bromobiphenyls are stable, but they are not compatible with oxidants.
Uses
It is used as an intermediate of organic synthesis and pharmaceutical. It also can react with norborn-2-ene to get 5-phenyl-1,2,3,4,4a,8b-hexahydro-1,4-methanobiphenylene, in synthesis of a novel trispirocyclic hydrocarbon. It is used as a reference compound to investigate extraction efficiency of solid-phase micro extraction fibers, based on methacrylic acid-trimethylolpropanetrimethacrylate copolymers.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 3037, 1979 DOI: 10.1021/jo01331a016
Tetrahedron Letters, 21, p. 845, 1980 DOI: 10.1016/S0040-4039(00)71521-8
General Description
Clear liquid. Insoluble in water.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Bromobiphenyl is sensitive to light. Low reactivity.
Fire Hazard
Flash point data for 2-Bromobiphenyl are not available. 2-Bromobiphenyl is probably combustible.
2-Bromobiphenyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromobiphenyl manufacturers
- Product
- 2-Bromobiphenyl 2052-07-5
- Price
- US $0.00/GK
- Min. Order
- 10g
- Purity
- 99.50%
- Supply Ability
- 10TONS
- Release date
- 2020-11-20
- Product
- 2-Bromobiphenyl 2052-07-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-09-01
- Product
- 2-Bromobiphenyl 2052-07-5
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30